Valerian has not been found to be habit forming, but should be used with discretion.  Though there are no known drug/Valerian interactions, the herb will intensify the effects of sedative medication. Therefore, any usage of Valerian with prescribed or over-the-counter sedatives is highly cautioned and discouraged. Some long-term users have experienced side-effects when they immediately stopped using Valerian. If Valerian has been taken for long-term relief, a gradual decrease in usage will eliminate such negative side-effects from occurring.

Under careful supervision, Valerian is safe for use by pregnant women, nursing mothers, infants, and children. Administration of Valerian to these particular groups can help to ease colic, convulsions, coughs, fevers, gas, and worms. The dosage of the herb should be moderate and should only be used when necessary.