Pregnant women should not use it as it is a strong emmenagogue.
Do not use if experiencing heavy menstral bleeding. Do not use during menstration.
If given for delayed onset of menstruation be sure the patient is not pregnant.
Do not give to children under two years of age.
Older children and adults over 65 years use low strength dosage and increase if necessary.
It should not be used by diabetics, due to its ability to cause weakness.
Psoralens in angelica cause sun sensitivity in fair skinned people.
"Psoralens also promote tumor growth, leading the authors of a report in the journal Science to advise against taking angelica internally. On the other hand, a recent animal study showed another angelica constituent (alpha-angelica lactone has an anti-cancer effect". (Castleman 47)
Do not use if experiencing loose stools or diarrhea.
Do not use with Warfarin (blood thinner). Angelica is considered a natural anti-coagulant.
Do not give to constitutionally weak people; those with chronic, low-grade infections.